XYLOCAINE® 2% WITH ADRENALINE (EPINEPHRINE) 1:80,000 DENTAL: Lidocaine Hydrochloride/Adrenaline. (Refer to full Data Sheet before prescribing). PRESENTATION: Sterile clear aqueous solution. Each millilitre contains lidocaine hydrochloride Ph. Eur. equivalent to lidocaine hydrochloride anhydrous 20mg and adrenaline bitartrate Ph. Eur. equivalent to adrenaline 12.5 micrograms. USES: Dental infiltration anaesthesia and all dental nerve block techniques. DOSAGE & ADMINISTRATION: Infiltration – usual dose is 1ml. Nerve block  usual dose is 1.5 to 2ml. Maximum dose is 25ml (500mg). Children and elderly or debilitated patients require smaller doses. CONTRAINDICATIONS, PRECAUTIONS, WARNINGS ETC: Contra-indications: Known hypersensitivity to amide anaesthetics. Intravenous use. Anaesthesia of fingers, toes, tip of nose, ears and penis. Precautions: Epilepsy, impaired cardiac conduction or impaired respiratory or hepatic function if high blood levels are anticipated. Hypertension, cardiac disease, cerebrovascular insufficiency, thyrotoxicosis, and those taking tricyclic antidepressants, MAOI’s or receiving potent general anaesthetics. Effect may be reduced if injected into inflamed or infected area. Use on one patient during one treatment only. Discard unused contents. Facilities for resuscitation should be available. Side effects: Rare and usually the result of excessive blood levels. Nervousness, dizziness, blurred vision, tremors, drowsiness, convulsions, unconsciousness, hypotension, myocardial depression, bradycardia, possibly respiratory or cardiac arrest. Allergic reactions are rare. Pregnancy and Lactation: Animal studies show no evidence of harm to foetus but do not use in early pregnancy unless benefit outweighs risk. PHARMACEUTICAL PRECAUTIONS: Store below 25ºC. PACKAGE QUANTITIES: Box of 100 cartridges. LEGAL CATEGORY: POM. FOR FURTHER INFORMATION CONTACT THE PRODUCT LICENCE HOLDER: DENTSPLY Limited, Building 1, Station Road, Addlestone, Surrey KT15 2PG