CITANEST® 3% WITH OCTAPRESSIN® DENTAL: Prilocaine Hydrochloride, Octapressin (felypressin). PRESENTATION: Sterile clear aqueous solution containing prilocaine hydrochloride 30mg/ml and Octapressin (felypressin) 0.03 i.u./ml. USES: Dental infiltration anaesthesia and all dental nerve block techniques. DOSAGE & ADMINISTRATION: Usual adult dose is 1–5ml. Children under 10 years 1–2ml. A dose of 10ml (5 cartridges) should not be exceeded. Elderly or debilitated patients require smaller doses. CONTRA-INDICATIONS, PRECAUTIONS, WARNINGS ETC: Contra-indications: Hypersensitivity to amide anaesthetics or any other of the solution’s components. Anaemia, congenital or acquired methaemoglobinaemia. Precautions: Caution must be taken to avoid accidental i.v. injection as it may give rise to rapid onset of toxicity. Use cautiously in the elderly, patients with epilepsy, severe or untreated hypertension, severe heart disease, impaired cardiac conduction or respiratory function, liver or kidney damage or poor health, if high blood levels are anticipated. Avoid injection if site is inflamed. Facilities for resuscitation should be available. Side effects: Extremely rare in dental practice and usually the result of excessive blood concentrations. Nervousness, dizziness, blurred vision, tremors, drowsiness, convulsions, unconsciousness, hypotension, myocardial depression, bradycardia and possibly respiratory or cardiac arrest. Allergic reactions. Methaemoglobinaemia; consider giving 1% methylene blue i.v. 1mg/kg over 5 minutes. Pregnancy: Use in caution during early pregnancy. Prilocaine enters mothers milk with no general risk at recommended doses. Interactions: With sulphonamides e.g. cotrimoxazole. Vasopressor properties of Octapressin should be considered. Observe caution when concomitant use with other amide-type local anaesthetics. PHARMACEUTICAL PRECAUTIONS: Store below 25ºC. PACKAGE QUANTITIES: Box of 100 cartridges £20.99. LEGAL CATEGORY: POM. PRODUCT LICENCE NUMBER: 04690/0028. FOR FURTHER INFORMATION CONTACT THE PRODUCT LICENCE HOLDER: DENTSPLY Limited, Building 1, Aviator Park, Station Road, Addlestone, Surrey KT15 2PG